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As expected, these signals were sensitive to imatinib treatment only in WT-Bcr-Abl-32D cells but not T315I-Bcr-Abl-32D cells, while ponatinib 27 treatment abolished these signals in both cell lines (Supplementary Fig

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Sometimes meaningful advances come from unexpected places, or from individuals willing to experiment on themselves long before the academic establishment takes notice

Full results, especially for deeper pigmentation and melasma , typically appear after six to eight weeks