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Review describing the physiological role of GLP-1 in the central regulation of feeding behaviour, as well the effects of pharmacological stimulation of GLP-1 pathways leading to alterations in CNS activity, reduced food intake and weight loss in obesity and T2DM

They can be utilized for diverse therapies, encompassing the encapsulation of enzymes such as L-asparaginase, dexamethasone, and thymidine phosphorylase, surface modification with targeting agents like biotin or antibodies, and RBC-inspired methodologies such as hitchhiking with nanocarriers

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Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus