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This occurs primarily through its influence on appetite regulation: Increased Satiety: By activating GLP-1 receptors in the brain, particularly in areas involved in appetite control, semaglutide enhances feelings of fullness and satisfaction after eating

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GLP-1 receptor agonists alter gastric emptying , slowing the rate at which food moves through the digestive system

But you shouldnt crush, split, or chew glipizide ER tablets

Less common but more serious risks include pancreatitis, gallbladder disease, and potential thyroid concerns