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50% for vitamin C and 40% for tretinoin

For first-time users, the published evidence base is strongest on topical at 1 to 2%

Possible B12 injection side effects tend to be mild and short-lived, and may include: Injection site pain, redness, or swelling Mild itching Brief diarrhea (less common) A feeling of warmth after the injection Serious side effects are rare

MIC B12 is typically contraindicated during pregnancy and lactation without explicit obstetric approval

In 2019, an internal medicine specialist could not find an objective cause for his B12 deficiency, and supplementation was stopped

That said, alcohol can impair judgment about injection technique, interfere with sleep and recovery, add empty calories that work against fat loss goals, and contribute to dehydration that may worsen side effects like headaches