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Smoking constricts blood vessels and reduces oxygen delivery to skin cells while generating additional free radicals
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Similar freckles may also occur in areas that are not exposed to the sun: Labial melanotic macules do not cause any symptoms but their appearance can be a concern to the patient
You can think of them like a lock outside a door
Choice of therapy in terms of usage, daily or weekly dosing and also tablet or injectable GLP-1 RA therapy also needs individual clinical decision making in partnership with the HCP and PwD
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