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PMID: 15665799

These pathways upregulate gene expression for collagen I and III synthesis, glycosaminoglycan deposition, and extracellular matrix remodelling enzymes through operations of considerable intricacy and documented efficacy

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City, which was founded by former Alnylam Pharmaceuticals CEO John Maraganore, is developing what they hope will be the next generation of gene-silencing drugs

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