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According to the NIH, several drugs have the potential to interact with L-carnitine

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Dosage Guidelines General Health & Fat Metabolism: 500-2,000 mg per day Exercise Performance & Recovery: 2,000-3,000 mg per day Best Practice: Divide total daily dose into smaller portions throughout the day L-Carnitine supplements taken with meals or in combination with carbohydrates for better absorption give the best results because the body can more easily take them in and utilize them

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Available from: Butler J, Shah SJ, Petrie MC, Borlaug BA, Abildstrm SZ, Davies MJ et al (2024) Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials

The performance of TMZ was not as predicted (Figures 5G, H)