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-Glutamylcysteine synthetase and active transport of glutathione S-conjugate are responsive to heat shock in K562 erythroid cells
Can you please tell me more about how
In the laboratory study Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo (Chen and colleagues, Proceedings of the National Academy of Sciences, 2007), pharmacologic ascorbate acted as a prodrug that formed hydrogen peroxide in the extracellular space but not in blooda route-dependent effect that oral dosing did not reproduce
However, sometimes the level of antioxidants produced naturally is not enough (either from illness, age, or genetics), or the amount of free radicals in the body is too high (especially if from an external source)
Why Sublingual Glutathione is Superior Higher absorption rate than oral capsules or powders
PMID: 36372047
