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Signal Transduction and Targeted Therapy , 9(1), 234
You should never increase a dose if you are not tolerating it well
Moreover, studies suggest that dual and triple receptor agonists may have additional effects on histological NASH features vs high-dose GLP-1R agonists alone, and that these may be independent of changes in body weight [78]
Galderisi, S
This happened long before any blood glucose could be detected
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