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Functional assessments reveal cartilage generated by FOXO4-DRI-pretreated chondrocytes displays significantly lower senescence levels compared to cartilage from untreated cells

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mTOR, a serine/threonine kinase frequently deregulated in cancer, is involved in various cellular processes and is therapeutically targeted in cancer treatment [127]

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Br.J Clin Pharmacol 2007;64(3):335-345