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Common Side Effects While uncommon, some people may experience mild side effects after receiving a B12 injection, including[17]: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling or numbness in the hands and feet These effects are typically short-lived and resolve on their own

Hopefully the dermatologist I see will have some familiarity or understanding of this

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Most people notice more energy within 2 to 3 days