Many individuals report feeling less exhausted during exercise, faster recovery times, and greater endurance
These figures come from vendor and community sources, not from a clinical trial of the fixed combination
Pulsatile GH patterns from CJC/Ipamorelin upregulate IGF-1 mRNA 2.8-fold more effectively than continuous exposure at equivalent total dose, according to Stanford research on JAK2-STAT5 signaling
however, it is also a precursor for the intracrine biosynthesis of potent androgens and estrogens in peripheral tissues that express the relevant steroidogenic enzymes, such as the skin (Labrie et al., 2003
Many protocols specify administration on an empty stomach because elevated glucose can blunt the GH-release response in research models
Our prior study infusing IGF-1 LR3 into normally grown late-gestation fetal sheep that resulted in increased fetal growth but decreased fetal insulin secretion used a dose of 6.6 gkg 1 h 1 based on an estimated fetal weight of 3.5 kg (final average LR3 dose 5.23 gkg 1 h 1 based on average actual fetal weight of 4.42 0.14 kg) (25)