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By bridging human and animal studies with translational clinical trials, this work positions KDS2010 as a promising first-in-class therapy, offering a novel paradigm for PTSD treatment

Also, VacA impairs GSH metabolism in gastric epithelial cells weakening their resistance against oxidative stress or cellular redox regulation by GSH [59]

Indeed, selective activation of PGC-1 within the hepatocytes protects the liver from lipids overload and progression to fibrosis, due to its ability to induce mitochondrial oxidative phosphorylation, fatty acids -oxidation and citrate cycle, while decreasing oxidative stress and promoting triglycerides excretion in the bloodstream 15

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