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Not only did primary analysis reveal reduced death from cardiovascular causes and non-fatal myocardial infarction overall, but prespecified secondary analysis also showed that, among patients with atherosclerotic disease and heart failure, there were reduced composite heart failure hospitalizations and cardiovascular deaths among patients taking semaglutide
37 CONCLUSION In consideration of clinical trials published thus far, oral semaglutide has demonstrated efficacy in terms of A1C and weight reduction when used as an addon to a variety of background glucose-lowering regimens in patients with T2DM and inadequate glycemic control
Like GST, its large size may interfere with target protein function enzymatic cleavage recommended for downstream structural or functional studies
More water means a weaker mix and easier-to-measure injections
