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Additionally, ABCG2 dysfunction appears to contribute to renal underexcretion of urate in patients with milder functional impairments, also classified by genotype

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Current guidelines from the American Society for Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity (IFSO) support consideration in patients with BMI 35 kg/m regardless of comorbidities, or BMI 30-34.9 kg/m with metabolic disease

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