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Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes

All of the velocities are given by Michaelis-Menten kinetics, with the K m values taken from the literature, and where available, from human data

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However, on the other hand most of the examined SNPs might lead to the loss of functionality of the different PLC domains including the core domain and therefore potentially disrupt downstream signaling pathways [33]

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