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Studies show that activation of the GLP-1 receptor in the brain reduces dopamine release from addictive substances such as nicotine and alcohol, leading to fewer cravings and reinforcement
According to the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID), none of the participants with autism met the diagnostic criteria for substance use disorder, bipolar disorder, or schizophrenia
The velocity and severity of the degenerative process most likely depends on the function of the opposite endplate
However, these issues deserve further investigation in controlled, randomized and probably multicentre trials to evaluate the clinical value and the appropriate dosage of L-carnitine in each of these conditions
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J Cytol Histol
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