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Oxidative stress then accelerates the aggregation of -synuclein which subsequently binds and sequesters available GSH, creating a destructive feedback loop of protein misfolding and antioxidant loss (Hoepken et al., 2007)

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This research was funded by the Shenzhen Longgang District Science and Technology Innovation Special Foundation (Project no

J Biol Chem (2008) 283(50):3526572