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The ability of GAs to induce ultrastructural changes to the mitochondria are among the earliest adverse mitochondrial effects described in the literature, including the observation of swollen and structurally aberrant mitochondria in rat subiculum following ISO exposure on postnatal day 7 (P7) (54, 55)

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Its important to note, that while these medications have been approved for specific medical conditions, they may also be used off-label for other purposes, such as weight loss

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