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While semaglutide itself doesnt demand fasting, hydration can help ease any digestive sensitivity some patients experience

In fact, all GLP-1 receptor agonists have some risk of gastrointestinal side effects namely, nausea, vomiting, diarrhea, and constipation due to how they work in the body

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Nausea is one of the most frequently reported side effects associated with retatrutide in clinical trials to date, as documented in the Phase 2 randomised controlled trial published in the New England Journal of Medicine in June 2023 (Jastreboff et al., NEJM 2023)

The most effective routine is usually the one that fits realistically into your life

Leave on for at least 30 minutes before removing