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In the nucleus, Nrf2 binds to antioxidant-response element (ARE), leading to enhanced expression of endogenous antioxidants, such as heme-oxygenase 1 (HO-1) and NAD(P)H quinone dehydrogenase 1 (NQO1) (Cuadrado et al

However, its important to consult with a healthcare professional to determine the optimal dosage tailored to your specific needs

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Further research to identify who may be most susceptible

In mammals, GSH conjugates are often further metabolized by hydrolysis and N-acetylation, either in the gut or in the kidney, to give N-acetylcysteinyl conjugates known as mercapturic acids, which are excreted in the urine