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Six controlled trials in approximately 900 participants are summarized in Stier et al

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Hypoxia at the injury site resolves faster with improved perfusion, removing the oxygen-deficit barrier to fibroblast metabolism

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Research using these peptides must adhere to appropriate institutional review and safety protocols including proper handling procedures, waste disposal, and experimental design safeguards

The aortas were then incubated in freshly prepared SA--Gal staining solution at pH 6.0 overnight at 37 C, according to the manufacturers protocol