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We confirmed both in vitro and in vivo that specific combination of ligands of different transporters, especially alanine and glutathione, is more efficient than single ligands to facilitate the penetration of nanocarrierss across the BBB [24, 32, 33, 42]

GHK-Cu's reported anti-inflammatory properties are based on preclinical findings and their clinical relevance in humans is uncertain

So through those deals, BPC-157 ended up inside a giant generics company that had little interest in pushing an unproven peptide through the rest of clinical testing, and it got shelved)

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Sandrin L, Tanter M, Gennisson JL, et al