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How GLP-1 receptor agonists can promote weight loss GLP-1 receptor agonists mimic a natural hormone our intestines release called glucagon-like peptide 1, which can promote weight loss via three actions: Suppressing appetite "The drugs 'talk' to our brain to encourage us to eat less and to be less preoccupied with food," explains Alexandra Sowa, MD , a dual board-certified obesity and internal medicine physician practicing in New York City, a clinical instructor of medicine at New York University, and author of The Ozempic Revolution
In rats given BPC-157, serotonin levels in the brain increase in specific regions while simultaneously decreasing in other regions, such as the hippocampus.[ref] A 2020 study found that BPC-157 reduced leaky gut syndrome by stabilizing gut permeability after NSAID use.[ref] Reducing leaky gut theoretically can affect the gut-brain axis and reduce inflammation
De Prisco, C
Journal of the International Society of Sports Nutrition, 22 (Supplement 2)
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By mimicking the bodys endogenous GLP-1, these drugs suppress appetite, slow gastric emptying, and influence reward mechanisms in the brain
