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While effective in the short term, extreme low-calorie diets are difficult to sustain
Mechanistically, capsaicin disrupts the Kelch like ECH associated protein 1 (Keap1)/Nrf2 interaction, promoting nuclear translocation of Nrf2 and transcriptional activation of antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) (101, 102)
BMJ 388 , e080679 (2025)
if youre using a vial, youll also need a syringe and needle (sold separately)
Without such context, its nearly impossible to distinguish true drugrelated events from unrelated background cases
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