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A heart that beats faster AND harder delivers more oxygen to working muscles
By catalyzing the carnitine/acylcarnitine exchange, CAC allows the import of fatty acyl moieties into the mitochondria where they are oxidized by the -oxidation pathway
A laxative effect or appetite changes may occur in case of overdose
They stimulate GH release through entirely different receptor pathways and can be combined for additive effect
The shorter half-life formulation is most common in current physician practice because it supports pulsatile GH release that more closely approximates endogenous physiology
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