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PMID: 19438432

Additionally, studies have revealed a sort of feed-back loop showing that sleep deprivation, even partial, makes the body even more susceptible to negative effects of toxic exposures

Additional well-designed, placebo-controlled clinical trials would be required to more fully characterize its pharmacokinetics, safety profile, and potential clinical relevance in human subjects

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These effects can include: abdominal pain chest pain cough dizziness eye pain irregular heartbeat ringing in the ears weight gain While some of these effects are merely uncomfortable, others are cause for concern

S.FridmanD