The primary cilia of nerve cells can sense and respond to the changes of the local extracellular environment
The integrated workflow encompassing data extraction, preprocessing, and analytical procedures is illustrated in Fig
The medication reduced up to 21% of body weight on average in clinical studies
It is important to distinguish between direct pharmacological effects and indirect consequences of treatment, such as anxiety related to dietary changes, rapid weight loss, or metabolic shifts
Over subsequent months, the weight loss mechanism compounds this effect, potentially requiring further dose adjustments as body weight decreases
43, 335367.10.1146/annurev-genet-102108-134201 42 MittovaV.TheodoulouF