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People who come off slimming jabs regain weight four times faster than dieters Slimmers who come off weight-loss injections such as Mounjaro or Wegovy can regain their lost pounds four times faster than those who stop conventional dieting and exercising, new research suggests

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Circulation 129(5):587597 van Bommel EJ, Muskiet MH, van Baar MJ, Tonneijck L, Smits MM, Emanuel AL et al (2019) The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial

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The landmark clinical dataset came from the Phase 2 trial led by Jastreboff et al., published in the New England Journal of Medicine in 2023