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The majority of renoprotective claims derive from rodent models (primarily db/db mice, streptozotocin-induced diabetes, or high-fat diet models), which exhibit fundamental differences from human DKD in gut microbiota composition, metabolic kinetics, and disease progression timelines
Management of uterine fibroids varies based on symptoms, size, location, and fertility desires
P-rank scores show that SGLT-2 inhibitors were ranked first in reducing renal outcome (100%) (Additional file 1: Table S2)
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