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Due to increased pollution, stressful lifestyles, and skin issues caused by these factors, many people today seek out medical-grade therapies that address the underlying causes of their skin issues rather than temporary solutions
doi: 10.3389/fphys.2016.00206 136 BinionDGRafieePRamanujamKSFuSFisherPJRiveraMTet al
To interrogate the mechanisms underlying NRF2-directed regulation of this core gene set, we compared mean promoter (1 kb restricted) ChIP-seq signal in A549 for NRF2, p300, as well as the histone marks H3K4me3 and H3K27ac, which are enriched at promoters and enhancers, respectively
