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Treatment of malaria with these drugs can cause (severe) hemolysis in G6PD-deficient individuals (i.e., males having a variant G6PD or heterozygous females with skewed The Importance of Reduced Glutathione in Detoxification Click The Image Reduced Glutathione NADPH produced in the oxidative phase of the pentose phosphate shunt maintains the cysteinyl sulfur of glutathione in the reduced state

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Vitamin C is one of the key cofactors the body uses to recycle that oxidised glutathione back to active duty

Glutathione Peroxidase / STransferase Assays Evaluate enzyme activity and inhibition in models of HO metabolism, organic peroxide reduction, and phase II detoxification of electrophiles

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