It becomes more likely as diabetes lasts longer, glucose control remains poor, and other risk factorssuch as hypertension and kidney diseaseaccumulate
When appetite decreases, it becomes easier to eat fewer calories without feeling deprived
Schrder H, Marrugat J, Vila J, Covas MI, Elosua R
Non-target lesion progression was found in 10.19% (11/108) patient of the GLP-1RA group and 22.12% (23/104) in the control group ( P = 0.037)
However, no cases of hypoglycemia were reported in phase 2 trials
Intramuscular injections are reserved for cases where oral treatment is insufficient, poorly tolerated, or where deficiency has caused neurological complications