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In models of hypertension, BPC-157 showed blood pressure-lowering effects, while in hypotensive states, it supported pressure normalization, suggesting homeostatic regulation rather than unidirectional cardiovascular effects

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Alternatively, pharmacological targeting of other players in the LE/Lys compartment that are intimately linked to Rab7 activity, including the mammalian target of rapamycin and vacuolar-type ATPase, or capable of modifying Rab7 activity through phosphorylation, palmitoylation and ubiquitination, could offer therapeutic opportunities [80, 81]

BPC-157 has become one of the most cited compounds in tissue-repair and regenerative-research literature, with over 150 peer-reviewed publications spanning tendon, ligament, muscle, gastrointestinal, vascular, and central nervous system injury models

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