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Their stable architecture reroutes PD-L1 from its normal recycling pathway to lysosomal degradation, sustaining checkpoint suppression for over 72 h and restoring T-cell cytotoxicity far more durably than conventional antibodies [19]

Repurposing of metformin and aspirin by targeting AMPK-mTOR and inflammation for pancreatic cancer prevention and treatment

Should not be used by pregnant or lactating women or children

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10.1089/ars.2017.7230 3