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While body weight and metabolic phenotypes remain the primary endpoints, the outcome spectrum is progressively extending toward lipotoxic load [e.g., hepatic fat and visceral adipose tissue (VAT)], inflammatory/cardiometabolic risk markers, and reproductive outcomes with higher clinical decision-making value, such as menstruation, ovulation, and pregnancy
ROS, reactive oxygen species
The rapid degradation of GLP-1 in humans is primarily since the alanine in position 8 is readily recognized and cleaved by dipeptidyl peptidase (DPP-4)
Cross-sectional survey of hypertension management in clinical practice in Japan: The Kanagawa Hypertension Study 2021 conducted in collaboration with Japan Medical Association Database of Clinical Medicine
Osteoarthritis: diagnosis and treatment
However, a follow-up of at least two years is recommended by some authors based on the cumulative findings in tumors occurring on the skull [15]
