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J Clin Endocrinol Metab, 2019
Both intrinsic and extrinsic apoptotic pathways are activated in AKI
It is derived from epithalamine, a naturally occurring peptide produced by the pineal gland
Tras la interaccin con el receptor, cada eje activa adenilil ciclasa mediante el acoplamiento de Gs, elevando los niveles intracelulares de AMP cclico (cAMP)
114 These actions fit nicely with the known anti-inflammatory and mitochondria protective effects of GLP-1 receptor agonists
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