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Further molecular mechanical analysis revealed that CM markedly enhanced VLDLR expression and decreased SREBP-1c and ApoB expression at the protein level in the liver, and significantly increased the protein expression of LXR/ABCG5 in the small intestine, as well as downregulation of the protein expression of PPAR and ATGL in the epididymal fat ( Pleurotus ostreatus polysaccharides fraction reduced liver triglyceride level through modulating the expressions of Dgat1, Ldlr, Nr1h4, Acat1, Srebf1, and Srebf2 in diet-induced hypercholesterolemic mice (58)

Accessed Apr 29, 2025.

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In contrast, the Clade II including a larger number of sequences and can be further divided into six groups: Group 1 to Group 6

Results showed berberine reduced body weight by 2.05 kg (approximately 4.5 pounds) and BMI by 1.04 kg/m compared to placebo or lifestyle intervention alone