Protection against paraquat treatment, locomotor impairment, shortened lifespan, and increased lipid peroxidation was observed in parkin RNAi flies treated with Persea americana peel extracts 30
10.1016/j.bbih.2021.100264 481 WuH.ChiouJ
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IM injections allow for slow absorption into the blood, providing a longer-lasting effect
TCF4 knockdown can promote ferroptosis and increase the cisplatin sensitivity of gastric cancer cells, 197 suggesting that abnormal activation of Wnt/-catenin pathway increases ferroptosis resistance in gastric cancer cells, offering a possible therapeutic strategy for enhancing chemotherapy sensitivity in patients with advanced gastric cancer
The excessive accumulation of lipid peroxides, ROS and PUFAs in the plasma membrane leads to cell membrane damage or ferroptosis