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PMID: 71

Trefts 2021)

Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice

While animal studies consistently demonstrate beneficial effects across diverse injury models and tissue types, the absence of adequately powered, controlled human clinical trials prevents definitive conclusions about efficacy in human disease

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Front Neurosci 15:695268 Qiu L, Li H, Li B, Ek J, Zhang X, Chen Y, Shao Z, Zhang J, Zhang J, Lin H (2024) Sevoflurane exposure in early life: mitochondrial dysfunction and neurotoxicity in immature rat brains without long-term memory loss