You are not swallowing a pill on an empty stomach every morning
Any appetite-related changes are secondary: as sleep improves, energy returns, and body composition shifts, patients naturally feel more motivated to support those changes with better nutrition
is now 7.2 mg per week as of March 2026, following FDA review of the STEP UP trial
Extensive clinical trials conducted during the drug's development, including the SUSTAIN programme, involved thousands of patients with type 2 diabetes followed over several years
1,2 For our skin, this leads to accelerated aging with wrinkles, pigmentation, dull skin and poor wound healing
It's not this huge burst of inflammation that you get from something like exercise where your body is responding to that with an anti inflammatory response