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In XIGDUO XR-treated patients with a diagnosis or strong suspicion of lactic acidosis, prompt hemodialysis is recommended to correct the acidosis and remove accumulated metformin (metformin HCl is dialyzable, with a clearance of up to 170 mL/min under good hemodynamic conditions)

2024 Sep;11:100121

Sterubin, a potent inhibitor of the oxytosis/ferroptosis pathway [57], has been studied as a neuroprotective compound and a potential therapeutic for age-related neurodegenerative disease [65]

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Medications are an important option when lifestyle changes alone are not enough, but they do not replace the need for healthy living, he said