[8] The scientific community has known for over 30 years that single-dose oral glutathione (150 mol/kg) produced no detectable plasma increases over 4.5 hours in healthy adults
Abbreviations CQ: Chloroquine CSCs: Cancer stem cells ER: Estrogen receptor-alpha GPxs: Glutathione peroxidases GSH: Glutathione HCC: Hepatocellular carcinoma hiPSC-MSCs: Mesenchymal stem cells drived from human induced pluripotent stem cells IBC: Inflammatory breast cancer IH: Isorhamnetin LOH: Loss of heterozygosity MnSOD: Manganese superoxide dismutase NAC: N -acetylcysteine PHGPx: Phospholipid GPx ROS: Reactive oxygen species TNBC: Triple-negative breast cancer TFAP2C: Transcription factor AP-2 gamma References Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
Thankfully, our bodies have a built-in defense system and glutathione is at the heart of it
S., Humbel, M., Fluder, N., Karampetsou, M
Further, pre-treatment with selenite significantly prevented the radiation-induced mutation of the hprt locus in AA8 cells