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Three factors tend to matter most: Follow-up consistency Medication with no follow-up may be considered to be guesswork

Skin Pigmentation & Tanning Melanotan II stimulates MC1R receptors in melanocytes, leading to increased melanin production . Research shows this results in darker skin pigmentation , which has been investigated for treating conditions like vitiligo and photosensitivity disorders . Why it matters: Increased melanin may help protect against UV-induced DNA damage and sunburn

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At that time, semaglutide was discontinued, and the patient had complete resolution of the rash by his follow up appointment 1 month later

It is not completely clear why semaglutide is associated with NAION, but researchers have a theory, Dr