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Early-onset cases of cobalamin C defect present with multisystem disease within the first year, with severe neurologic (eg, lethargy, hypotonia, microcephaly, seizures, stroke, neurodevelopmental delay), ocular (eg, rapidly progressing maculopathy with severe photoreceptor and ganglion cell loss), hematological, renal (eg, atypical hemolytic-uremic syndrome, renal arteriolar and glomerular thrombotic microangiopathy), gastrointestinal (eg, vomiting, diarrhea, feeding difficulties), cardiac, and pulmonary manifestations (eg, apneic episodes) (147
What are IM Boosters
Wash your hands thoroughly with soap and water
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The following are the recommended daily allowances for children and adults of different ages: Avoid consuming large amounts of alcohol during vitamin B12 injection treatment
Cobasorb test (the patient is given a small dose of oral B12 and then tested to see if it increases the B12 in their blood) 4 d
B12 promotes collagen production, which is essential for tissue repair, allowing your skin to heal faster and with less scarring
