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Clinical trials have explored a range of doses to assess efficacy and safety, with regimens tailored to therapeutic goals and patient response

Whilst mini-G s recruitment was also reduced, the impact on -arrestin-2 recruitment was greater, with biased agonism confirmed by the operational model approach and on the basis of efficacy differences (Onaran et al ., 2017)

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Whilst mild injection site reactions are common and typically self-limiting, certain presentations warrant prompt clinical assessment

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