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This becomes even more relevant when combining AOD-9604 with training
Independent predictors of amputation identified in the study included prior amputations, male sex, non-Asian ethnicity, history of PAD, history of neuropathy, albuminuria, and elevated HbA1c levels at baseline.38 While this finding was not replicated in other randomized clinical trials on SGLT-2 inhibitors, it is recommended to conduct a thorough screening for risk factors for amputations when initiating SGLT2 inhibitors
Using a maintenance dose: For some people, reducing to a lower maintenance dose indefinitely or switching to a different medication can provide the extra support needed to maintain their progress long term
For someone on a GLP-1 who is eating fewer calories because their appetite is suppressed, the body is already looking for tissue to break down for energy
It can cause side effects such as nausea, vomiting, stomach upset, heartburn, diarrhea, and seizures