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In fact, for many people, the best sign that a supplement is working is simply a gradual sense of improved resilience, better recovery from exercise, and more consistent energy levels

Chernoff R: Protein and older adults

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Clinical evidence comes in tiers: mechanistic studies (does the molecule do what it should at the cellular level?), animal studies (does it produce the expected effect in a living organism?), and human trials (does it actually work on the people who will use it?)

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Glutathione in cellular redox homeostasis: association with the Excitatory Amino Acid Carrier 1 (EAAC1)