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while glycaemic efficacy diminishes at lower eGFR levels, some agents are licensed for heart failure and chronic kidney disease at eGFRs below 30 ml/min/1.73m

The treatment group showed significant reductions in body weight (approximately 5% loss) and white adipose tissue mass (35% reduction) compared to control animals, despite no changes in food intake

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ISSN 1743-9191

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