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SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis

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135 Torres et al found that melatonin decreases the levels of oxidative stress markers and increased both enzymatic and nonenzymatic antioxidant capacities in the lung

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For instance, GSH, composed of cysteine, glycine, and glutamic acid, accounts for the majority of cellular antioxidants to create highly reductive TME and is involved in tumor initiation, progression, and metastasis (Harris et al., 2015

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This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 27,99 / 30 days cancel any time Subscribe to this journal Receive 1 digital issues and online access to articles 118,99 per year only 118,99 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

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PMC 2722857

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A., & Smolenski, R

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